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Pathophysiological aspects of hypertension

Alvin P. Shapiro

pp. 35-40

The psychophysiological aspects of hypertension comprise the set of blood-pressure responses which result from noxious stimuli of behavioral origin. Such responses may play a role in the predisposition, precipitation, and perpetuation of hypertension, and in turn their alleviation may represent a therapeutic modality in its management. However, these psychophysiological factors must be considered in the context of hypertension as a multifactorial disorder; it is a disturbance in the complex regulatory mechanisms which control the relationship between the circulating fluid volume (i.e., cardiac output) and the space in which it circulates (i.e., peripheral resistance). The system includes neural, renal, hormonal, and cardiovascular mechanisms, which in turn influence each other through multiple feedback devices to maintain normal blood pressure and oxygen delivery to peripheral sites in the body. The psychophysiological responses operate through any and all of these basic mechanisms to produce their impact.

Publication details

DOI: 10.1007/978-94-011-7289-9_3

Full citation:

Shapiro, A. P. (1982)., Pathophysiological aspects of hypertension, in W. E. Fann, I. Karacan, A. D. Pokorny & R. L. Williams (eds.), Phenomenology and treatment of psychophysiological disorders, Dordrecht, Springer, pp. 35-40.

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